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Symbol
Name
ID

Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
MGI:98325

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Anemia	Microcytic anemia	Bone-marrow foam cells	Sea-blue histiocytosis	Thrombocytopenia	Splenomegaly
Disease(s) Associated with SMPD1	Anemia	Microcytic anemia	Bone-marrow foam cells	Sea-blue histiocytosis	Thrombocytopenia	Splenomegaly
Niemann-Pick disease type A
Niemann-Pick disease type B

Mouse Phenotypes		increased macrophage derived foam cell number	hepatosplenomegaly	enlarged spleen	abnormal granulocyte physiology
Availability	Mouse Genotype	increased macrophage derived foam cell number	hepatosplenomegaly	enlarged spleen	abnormal granulocyte physiology
	Smpd1^tm1Esc/Smpd1^tm1Esc
	Smpd1^tm1Wst/Smpd1^tm1Wst

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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